FOLH1 and neoplasm: Importantly, the lowest blood activity was determined for 177Lu-Ibu-DAB-PSMA, which resulted in up to 1.3-fold increased tumor-to-blood AUC ratios compared to the other ibuprofen-derivatized radioligands (p>0.05) and a 1.6-fold increased tumor-to-blood AUC ratio compared to the previously published value for 177Lu-PSMA-ALB-56 (p<0.05) (Figure 4; Supplementary Material, Table S8) 29.