High YY1 expression was associated with poor outcome of patients with NB (GSE16476 and GSE62564, P=2.6×10-4 and P=4.9×10-12), breast cancer (P=3.1×10-3), endometrial carcinoma (P=6.1×10-3), glioma (P=1.6×10-11), head and neck carcinoma (P=1.2×10-2), lung cancer (P=5.5×10-3), lymphoma (P=1.0×10-3), pancreatic cancer (P=1.4×10-4), or renal clear cell carcinoma (P=3.0×10-4, Figure 6B and Figure S12B-C). This evidence concerns the gene YY1 and familial pancreatic carcinoma.