ETV4 and colorectal carcinoma: The TCGA dataset analysis revealed that ETV4 and ETV5 were significantly upregulated across all stages of CRC (Fig. 3a), and that ETV4 expression was notably increased in the CRC samples compared with that in the normal colon tissues among the PEA3 group genes (Fig. 3a), consistent with previous findings that overexpression of ETV4 was frequently observed in samples from patients with CRC [39, 44, 45].