Furthermore, autophagy has been found to be important in zebrafish fin26 and skeletal muscle27–29 regeneration, while very recent studies have proven the zebrafish as a unique and useful model to study autophagy-related cardiomyopathies and their association to the mechanistic target of rapamycin (mTOR) signaling pathway30–32. This evidence concerns the gene MTOR and cardiomyopathy.