Colitis is characterized by expression of both pro-inflammatory cytokines, including tumour necrosis factor-alpha (Tnfa), interleukin 1-β (Il1b), and interleukin 17 A (Il17a), and anti-inflammatory cytokines, including interleukin 10 (Il10) and interleukin 22 (Il22). The gene discussed is TNF; the disease is colitis.