Li et al. found that hyperglycemia and hyperlipidemia enhanced the expression levels of ox-LDL receptors (e.g., LOX-1) in ECs49–51; this can induce apoptosis, suggesting that the effects of HG and lipids on inhibiting proliferation of ECs may be related to the induction of apoptosis of ECs. Here, OLR1 is linked to Hyperglycemia.