Alkaline haemoglobin electrophoresis method was carried out to detect the coinheritance of hemoglobinopathy mainly the sickle cell anaemia, heterozygous B-thalassemia, Hb H or Hb Barts, using SAS-MX Alkaline Hb-10 kit (Helena Bioscience Europe), then the types and percent of Hb were measured by densitometry method. The gene discussed is GSTM1; the disease is sickle cell disease.