As mentioned above, EBV infection status is determined by testing more than one parameter to accurately distinguish acute from a past EBV infection, thus, considering that IgM anti-VCA measurements were not included in this study, as the authors stated, “because only a few samples were positive, and IgM-positive patients preferentially presented NAG, we did not continue that analysis”, based on the available data, the proportion of patients with an active EBV infection is unknown. The gene discussed is CD40LG; the disease is Epstein-Barr virus infection.