Corresponding with preserved insulin signaling in cells co-incubated with palmitate and WPH, protein levels of Glut4, the major insulin-sensitive glucose transporter in skeletal muscle, were maintained in this group while palmitate treatment led to decreased Glut4 levels in BPI, BPH, and WPH groups (Figure 4C,D). The gene discussed is INS; the disease is benign prostatic hyperplasia.