From the GO processes the function of each gene is summarised in Table 2, with the most promising candidate genes associated with treatment response being those involved in transcriptional regulation (ATRX), tumour suppression (TP53, PTEN and CDKN2A), proliferation and survival (IDH1, PKHD1, PIK3R1 and PIK3CA). Here, PIK3CA is linked to neoplasm.