IDH2 and acute myeloid leukemia: Other drugs/agent in phase testing in combination with CPX-351 are Venetoclax, a BCL-2 inhibitor with antineoplastic activity [167], or Enasidenib, an inhibitor of isocitrate dehydrogenase 2 (IDH2), approved in the United States for the treatment of adult patients with mutant-IDH2 relapsed or refractory (R/R) AML [168].