VEGFA and cancer: It can lead to an increased expression of Bax and p53 (pro-apoptotic proteins), suppression of vascular endothelial growth factor (VEGF) and hypoxia-inducible factor 1-alpha [HIF-1α] (angiogenesis factors), reduction of the pro-inflammatory responses, induction of autophagy and improvement of drug efflux in drug resistance cancer cells [13,14,15,16,17].