Concerning 18F-FDG PET radiomic analysis and PD-1/PD-L1 expression, a team found in 53 oropharyngeal or hypopharyngeal cancer patients that several PET-derived textural features, describing the organization of tumor pixels, can provide information to determine tumor PD-L1 expression in head and neck carcinoma [49]. Here, CD274 is linked to head and neck carcinoma.