NFKB1 and mastitis: Recently, it was shown in a mouse model of mastitis that the inflammatory process induced by LPS administration in the mammary gland is also closely related to induction of endoplasmic reticulum (ER) stress in mammary tissue and that attenuation of ER stress by a secondary plant metabolite protects from LPS-induced mastitis by inhibiting the pro-inflammatory NF-κB signaling pathway [15].