For example, FOXM1 and MYBL2 may be key regulators of cell proliferation in non-small lung cancer [21], MYBL2 is associated with cell proliferation in liver cancer cells [22], TPX2 may be a potential therapeutic target in genomically unstable cancer cells [23], and PLK1 may contribute to autophagy in osteosarcoma cells [24]. The gene discussed is PLK1; the disease is osteosarcoma.