HMGCR and type 2 diabetes mellitus: Swerdlow et al. [18] assessed associations between SNPs (rs17238484 and rs12916) of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) and the prevalence and incidence of T2DM by meta-analysis in 223,463 individuals from 43 genetic studies.