Excitingly, contrary to findings reported for other solid tumors, such as gastric cancer [15], lung adenocarcinoma [20], and colon cancer [21], studies by Anne Gomez-Brouchet et al. [22] indicated that the presence of CD163-positive M2-polarized macrophages is essential for inhibiting OS progression, which represents an important discovery. This evidence concerns the gene CD163 and lung adenocarcinoma.