For this purpose, SNHG12 was overexpressed in N3S and Pri GBM cells (TMZ-sensitive cell lines, Additional file 6: Figure S1b–c and Fig. 3a) and we tested the apoptotic rate of these TMZ-sensitive cells following transduction with either pcDNA-SNHG12 or an empty vector. This evidence concerns the gene SNHG12 and glioblastoma.