In addition, a high level of SNHG12 was found in two other GEO datasets (GSE59612 and GSE104267) and SNHG12 expression was found to be relatively high in the recurrent GBM tissues analyzed in this study compared with the primary GBM tissues in GSE7696 (this dataset describes samples of recurrent GBM tissues after receiving TMZ treatment) (Additional file 6: Figure S1d). Here, SNHG12 is linked to glioblastoma.