METTL3 and colorectal carcinoma: In CRC, a recent research has verified that METTL3 could promote cell self‐renewal, stem cell frequency and migration through an m6A‐IGF2BP2‐dependent mechanism.37 However, another study showed that METTL3 could suppress colorectal cancer proliferation and migration through p38/ERK pathways.38 Therefore, the role of METTL3 in CRC might be controversial and need to be further explored.