Moreover, studies indicated that HSP70 is involved in the pathogenesis of hypertension and associated diseases such as coronary heart disease, atherosclerosis, ischaemic stroke, Parkinson’s disease, high-altitude illness and the forth, and there were high levels of HSP70 in serum, plasma and placental tissue of PE patients [17,19,20]. This evidence concerns the gene HSPA1A and coronary artery disorder.