ERBB2 and breast carcinoma: Integrating these approaches is predicted to be even more powerful (Chakraborty et al., 2018; Manem et al., 2018) (Table 1) For instance, a genomic/transcriptomic/proteomic combined approach has confirmed the existence of the known molecular subtypes (LumA, LumB, HER2+, and BL) of breast cancer (Cancer Genome Atlas Network, 2012) as well as allowing identification of novel therapeutic targets in PDX models (Huang K. L. et al., 2017).