CD11b+ DCs (both Ly6C+ and Ly6C−) were the main infected DC populations in both the footpads and lymph nodes at week 4 post-infection, and numbers of infected CD11b+ DCs were greater in CD11ccreIL-4Rα−/lox mice compared to littermate controls (Figures 2C,D). This evidence concerns the gene ITGAM and infection.