UBE2C and breast carcinoma: However, univariate, Kaplan–Meier, and multivariate analyses of subgroups according to LN status revealed that high UBE2C expression was associated with significantly shorter DFS, DMFS, and OS in breast cancer with pN0 and pN1 tumors but not in pN2/N3 tumors (P < 0.05, Supplementary Table 1, Figure 1, and Table 2).