MGMT and glioblastoma: In respect of the MGMT methylated status and the better outcome, our results are in line with the main series published in literature (7, 19) with a median OS of 19.5 months for patients with a MGMT methylated GBM vs. 14 months for patients with an MGMT unmethylated GBM and 2 months more of PFS between the two groups.