In NSCLC, Th17 cells have been widely reported to promote tumor progression: levels of IL-17, a major cytokine from Th17 cells, are significantly higher in NSCLC patients than non-cancer patients (186), and high levels of IL-17 are positively related to lymph node metastasis and advanced staging (106). The gene discussed is IL17A; the disease is metastatic malignant neoplasm in the lymph nodes.