Tassi et al. (54) employed RT-PCR to analyze MGB-2 expression in EEC tumors with different grades of differentiation and found this gene was expressed in 10 of 11 grade 1 (91%), 16 of 17 in grade 2 (94%), and 6 of 22 grade 3 (27%) EEC cases. The gene discussed is SCGB2A1; the disease is exstrophy-epispadias complex.