Compared to normal tissue samples, ZC3H13, METTL14, and YTHDF2 were down regulated, while FTO, ALKBH5, WTAP, METTL3, YTHDC2, KIAA1429, and RBM15 were up regulated in ccRCC tissue samples (Figure 2D). Here, METTL3 is linked to nonpapillary renal cell carcinoma.