YTHDF2 and nonpapillary renal cell carcinoma: Firstly, 10 of 13 m6A RNA methylation regulators were identified as playing important roles in the development of ccRCC, including ZC3H13, METTL14 and YTHDF2, FTO, ALKBH5, WTAP, METTL3, YTHDC2, KIAA1429, and RBM15.