Furthermore, downregulating the expression of linc00662 in SW480 and Caco-2 cells significantly reduced AVL9 mRNA levels in the two cell lines (Figures 6I, J), while miR-497-5p inhibitor (Figure S6) restored AVL9 expression in the linc00662-downregulated CRC cells. This evidence concerns the gene AVL9 and colorectal carcinoma.