Furthermore, elevated CXCL8 expression is associated with the induction of angiogenesis as well as increased proliferation, invasion and migration of tumor cells (Singh et al., 1999; Inoue et al., 2000; Zhu et al., 2004; Matsuo et al., 2009; Fernando et al., 2011; Ning et al., 2011; Roshani et al., 2014; Liu et al., 2016). The gene discussed is CXCL8; the disease is neoplasm.