CXCL8 and cancer: The C-X-C motif chemokine ligand 8 (CXCL8), which is a member of the CXC chemokine family, is a pro-inflammatory cytokine produced by neutrophils, macrophages, endothelial cells, and cancer cells (Kitadai et al., 1998; Inoue et al., 2000; Konno et al., 2003 ).