TNF and malaria: KEGG pathway analysis provided the potential function cluster of DEGs, showing that the up-regulated DEGs were clustered in malaria, human T-cell leukemia virus type I, the way of malignant tumor, legionella infection disease, TNF signaling pathways, and T-cell receptors signaling pathways (Figure 3A), whereas the down-regulated DEGs were significantly concentrated in axon guidance and microRNAs in cancers (Figure 3B).