However, due to limited research on OSCC, only one study revealed that the expression of CTNNB1 and ETS1 in tumor tissues was higher than that in normal tissues, with 2.285 and 2.111 fold change, respectively, while no difference was found in the expression of NOTCH1 and JUN genes in the two tissues (Figure 6). This evidence concerns the gene NOTCH1 and neoplasm.