An enhanced expression of CD206 together with HLADR, CD86, and CD80 on 1,25(OH)2D3-polarized cells could suggest that antigen-presentation and co-stimulation is improved by vitamin D. Interestingly, also Chlamydia infection of polarized MDMs (8) or murine bone-marrow derived macrophages (38) was considerably lower in M1 compared with M2 cells. The gene discussed is CD80; the disease is chlamydia infectious disease.