miRNA-K5 and miRNA-K9 associated with Kaposi's sarcoma target myeloid differentiation primary response gene-88 (MyD88) and Interleukin 1 receptor-associated kinase 1 (IRAK1), which further reduces the expression of inflammatory cytokine and clearance by the immune system (21). Here, IRAK1 is linked to Kaposi's sarcoma.