Surprisingly and in disagreement with the literature, we found that Irf5 deletion in CD11c+ cells did not affect the Th1 immune response; indeed, comparable frequencies of IFNγ+ CD4 T cells were observed at various time points after infection in the liver of both groups of mice (Figures 4A,B; gating strategy in Supplemental Figure 1A). This evidence concerns the gene ITGAX and infection.