Finally, elevated expression of pro-inflammatory cytokines including IFN-β, IFN-γ, IL-6, IL-12p40p70, monocyte chemotactic protein 5 (MCP5), stem cell factor (SCF), soluble tumor necrosis factor receptor I (sTNFRI), and vascular endothelial growth factor (VEGF) was detected in PR8-infected cells at 12 h post infection (hpi) compared to mock cells. This evidence concerns the gene IFNB1 and infection.