Furthermore, we also found that OPN, IFNγ, IL-10, IL-8 concentrations, and NLR did not correlate with BMI, cholesterol and triglyceride levels, which supports the theory that apart from antipsychotic therapy and immune factors the genetics and lifestyle of the patients could also have a role in obesity and altered levels of blood fats (30). Here, SPP1 is linked to obesity due to melanocortin 4 receptor deficiency.