Our aim also was to measure the concentrations of signature cytokines interferon gamma (IFNy) for Th1 cells, interleukin 10 (IL-10) for Th2 subset, and interleukin 8 (IL-8) for Th17 lymphocytes, respectively, in serum samples and to calculate NLR from blood counts to evaluate the relevance of T-helper subtypes and NLR in the assessment of the severity of schizophrenia. This evidence concerns the gene IFNG and schizophrenia.