Our result showed that dl-NBP treatment increased the number of RECA-1 positive vessels after focal transient ischemic stroke, accompanied by upregulated HIF-1α and VEGF, suggesting that dl-NBP treatment may increase the number of RECA-1-positive vessels though upregulating HIF-1α and VEGF after focal transient ischemic stroke in non-hypertension patients. This evidence concerns the gene VEGFA and hypertensive disorder.