In the SVZ region, similarly, CCH-induced impaired neurogenesis, as it was revealed that the BrdU+/NeuN+ cells declined to 61.89% ± 8.27% of the sham group (P < 0.01, Figures 6D, F), which was significantly reversed by thioperamide to 97.78% ± 16.23% (P < 0.01, Figures 6D, F). This evidence concerns the gene RBFOX3 and columnar cell hyperplasia of the breast.