Moreover, the patients with overt NAFLD had higher systolic blood pressure (SBP), waist-to-hip ratio, HbA1c, total cholesterol, LDL-cholesterol, aminotransferase (AST), ALT, GGT, WBC count, fasting insulin, and HOMA-IR than the normal subjects. This evidence concerns the gene INS and metabolic dysfunction-associated steatotic liver disease.