CD4 and cryptosporidiosis: Annually, approximately 8500 cases of cryptosporidiosis are reported in the United States19; while Brazil and Africa reported that the prevalence of cryptosporidiosiswas 3.5% to 22.4% and around 50% from PLHIV with a low CD4+ cells,respectively.20, -22 The incidenceof Cryptosporidium infections was found to be 10.1% of PLHIV inChina,23,24 7.6% cases of cryptosporidiosis were reported to beHIV-seropositive patients in Iran,25 while 71.4% of that prevalence were associated with diarrhea.