Accumulating evidence indicates that LRH‐1 participates in the pathogenesis of multiple tumors including pancreatic (Benod et al., 2011; Petersen et al., 2010), breast (Thiruchelvam et al., 2011), gastric (Wang et al., 2008), and colon cancer (Schoonjans et al., 2005). The gene discussed is NR5A2; the disease is malignant colon neoplasm.