Because LRH‐1 has been proposed as a potential target of GATA6 (Sulahian et al., 2013) plus our recent work found that knockdown of LRH‐1 expression could decrease the stemness in the GATA6‐overexpressing human CRC cells (Lai et al., 2020), we first analyzed whether LRH‐1 is a direct target gene of GATA6. The gene discussed is NR5A2; the disease is colorectal carcinoma.