In line with this hypothesis, we experimentally defined functional correlates of this effect, as me2‐DIPH negatively modulates transport capacity of the drug efflux pumps MRP2, MRP3, and MRP5 (Fig. 5), which export CP and mediate platinum resistance, as demonstrated for ovarian cancer (Liedert et al., 2003; Materna et al., 2005; Surowiak et al., 2006). The gene discussed is ABCC5; the disease is ovarian carcinoma.