Univariate models revealed that smoking history (hazard ratio [HR] = 3.556, P = 0.011), preoperative CEA level (HR = 1.043, P = 0.007), radiologic appearance with solid‐dominant tumor (HR = 3.582, P = 0.018), clinical stage (HR = 2.143, P = 0.005), PL2 invasion (HR = 9.320, P < 0.001), poorly differentiated tumor (HR = 5.794, P < 0.001), tumor presentation of ALI (HR = 16.236, P < 0.001), and high grade predominance of adenocarcinoma (HR = 7.506, P < 0.001) significantly increased the risk of DFS. Here, CEACAM5 is linked to neoplasm.