In order to expand the significance of our finding in vivo, we injected the A549 (mutant KRAS) and HCC95 (wild-type KRAS, ACSL3-dependent) NSCLC cells into immunocompromised NOD scid gamma (NSG) mice, previously transduced with a control or shRNA against LPIAT1. This evidence concerns the gene ACSL3 and non-small cell lung carcinoma.