To test the ability of α-GD2 TMs to redirect UniCAR NK-92 cells to GD2-expressing tumour cells, GD2-positive JF Luc neuroblastoma cells were co-cultured with UniCAR 28/ζ NK-92 cells at different effector to target (E:T) ratios in the presence or absence of either the scFv- or IgG4-based TMs at molar concentrations representing comparable numbers of GD2-specific binding moieties and E5B9 epitope tags. The gene discussed is MIR4435-2HG; the disease is neuroblastoma.