Thyroid hormone replacement therapy, proteinuria with urine protein/creatinine ratio above 3000 mg/g, tacrolimus levels above 12 ng/mL, CRP values above 5 mg/mL and arterial hypertension as potential factors influencing thyroid hormones and eGFR had no significant effect at any time point and interval (Table 5). The gene discussed is TG; the disease is Hypertension.