IDH1 and anaplastic astrocytoma: As compared with the IDHmt group, survival outcomes in the IDHwt group were poor, similar to those in patients with anaplastic astrocytoma, IDH-wildtype (5-year OS: 47.5%) and worse than those in patients with anaplastic astrocytoma, IDH-mutant (5-year OS: 71.6%) in our previous study8.