ASIC5 and cerebellar ataxia: Further tying a change in electrical activity to ataxia in the Asic5 KO mouse are the findings in Figs. 4, 5 and 7 demonstrating that a slowed maximum depolarization rate and consequent increase in interspike interval may be the cellular causes of the decrease in intrinsic excitability and spontaneous firing observed in type II UBCs from the Asic5 KO mouse.