Interestingly, there were no significant differences in CCL5 and CXCL10 levels between CHC patients and AC patients (p = 0.4764 and 0.0964), but sCD14 and sCD163 were significantly higher in CHC patients compared to AC (p = 0.0346 and 0.0489, respectively; Fig. 1a). Here, CCL5 is linked to cryohydrocytosis.