IFNG and neoplasm: Levels of IFN-γ and IL-12 were significantly elevated in L. casei-fed mice at the endpoint of the probiotic administration (d13 from start) 3 days post CT26 inoculation in accordance with a study by Chiba et al [18], and increased IFN-γ production in PP was persistent at the end of the experimental procedure, 7 days after tumor establishment.