As shown by Allen et al. [49], CCL3 secretion in the tumor results in higher IFN-γ production and as mentioned before, IFN-γ further enhances accumulation of molecules contributing to targeted migration and tumor specific cytotoxicity, such as CXCL9, CXCL10 and CXCL11 [50], especially in combination with CCL5 [51], which was also potently increased in our experiments. The gene discussed is CXCL10; the disease is neoplasm.