Since then, no other family with this translocation has been identified and the role of DISC1 in major psychiatric disorders is disputed [64]: Genome-wide linkage, CNV, and common variant analysis do not support DISC1′s role as a common bona fide risk gene in psychiatric disorders, but suggest that variations in DISC1 affect only a few individuals, families, or ethnic groups [65]. The gene discussed is DISC1; the disease is psychiatric disorder.